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KMID : 0389519990060020110
Sleep Medicine.Psychophysiology
1999 Volume.6 No. 2 p.110 ~ p.115
The Effect of Mandibular Repositioning Device on Airway Size and Airway Collapsibility in Obstructive Sleep Apnea Syndrome : Cine CT during Sleep
Hong Seung-Bong

Kyung Seung-Hyun
Na Dong-Kyu
Son Young-Ik
Park Young-Chel
Abstract
Objectives : To investigate the effect of mandibular repasitioning device on airway sige and airway collapsibility in patients with obstructive sleep apnea syndrome (OSAS).

Methods :Cine CT with polysomnographic monitoring was performed during sleep in nine(OSAS) patients before and after mandibular repositioning device (MRD) application. Axial CT images were obtained in five upper airway levels (retropalatal-high, retropalatal-low, retroglossal, epiglottis, and hypopharynx levels). In each airway level,
one axial CT image was obtained during sleep apnea period and 10 serial axial CT images were scanned every 1 second during normal sleep breathing. After searing MRD, all CT images were obtained by the same method. The cross-sectional areas of airway were measured by automatic tracing method. The changes of minimum airway size and maximum airway size after MRD were evaluated. The airway collapsibility was calculated before and after MRD.

Results : During sleep apnea, the airway of retropalatal-low level was the most frequently narrowest site. During normal sleep breathing the minimum airway size was increased significantly after MRD at retropalatal-low level(p=0.011). The mean airway collapsibility was the highest at retropalatal-low level. MRD decreased the airway collapsibility significantly at retropalatal-low level (p=0.021) and epiglottis level (p=0.038).

Conclusions : The enlargement of the minimum airway size and decreased airway collapsibility may be the therapeutic mechanism of MRD in obstructive sleep apnea.
KEYWORD
collapsibility, Obstructive sleep spnea syndrome, Mandibular repositioning device, Cine CT, Airway size, Airway collapsibility,
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